He and younger brother Kaiba Mokuba were adopted from an orphanage by Gozaburo Kaiba. Mutou Yuugi's biggest rival and largely believed to be the anti-hero of Yu-Gi-Oh! Duel Monsters. Arrogant and power-driven, he believes that he is the best duelist in the world. Seto took over his stepfather's company Kaiba Corporation at a young age and became the president of "Kaiba Corp", which is the biggest gaming company in the world of Yu-Gi-Oh! and among the most influential in the United States.
His signature monster is the Blue-Eyes White Dragon.