A game journalist from the gaming blog Kotaku asked an SNK spokesperson if this game would be released in the US, and the response was "...this title is only for Japanese market. We do not have any plan for localize to the other versions.", despite the game originally having official sites in English, Chinese, and Korean. These were taken offline when the Japanese language site was rewritten to focus on the upcoming sequel game.
The player assumes the role of a junior high school student who is asked by an angel to locate a witch that has sneaked into her school. In order to find the witch, she must search the suspects' bodies for a "witch mark." The preferred method is by using touch (using the stylus to guide her hands).
A sequel titled Doki Doki Majo Shinpan 2 Duo was released 31 July 2008, and a third game titled Doki Majo Plus was released on July 30, 2009.